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Sildenafil citrate, commonly known by the brand name, is a prescription-only medicine used to treat erectile dysfunction (ED) in adult men. It works by improving blood flow to the penis, helping to achieve and maintain an erection during sexual activity.

Dosage and Administration

Sildenafil is available in 25mg, 50mg, and 100mg strengths.

  • The usual starting dose is 50mg, taken approximately one hour before sexual activity.
  • Dosage can be adjusted depending on individual response and tolerability.
  • Take only one tablet in 24 hours, with or without food.
  • Avoid grapefruit juice, as it can increase the risk of side effects.
  • A high-fat meal may delay onset of action.

Effectiveness

Sildenafil has been shown to be effective in up to 80% of men with ED, with effects typically noticeable within 30 to 60 minutes, and lasting for up to 4–5 hours.

Side Effects

Common side effects include:

  • Headache
  • Flushing
  • Nasal congestion
  • Indigestion

Less common but serious effects include visual disturbances, hearing changes, or prolonged erections. Seek medical attention if severe or persistent side effects occur.

Contraindications

Sildenafil should not be used by those:

  • Taking nitrates for chest pain
  • With severe heart or liver conditions
  • Under 18 years of age
  • With certain medication interactions (e.g. alpha-blockers, antifungals, antibiotics)

Interactions

Inform your doctor of all medications and supplements before use. Interactions may occur with:

  • Nitrates
  • Alpha-blockers
  • Some antibiotics and antifungal medicines

Alcohol and Heart Conditions

Avoid excessive alcohol while taking sildenafil, as it can lower blood pressure and increase side effect risk. Use with caution if you have any heart-related conditions.

Availability and Cost

Sildenafil is available by prescription only in the UK.

  • Generic versions are more affordable than branded Viagra.
  • Supplied by licensed UK pharmacies such as Online Chemist.
  • Avoid counterfeit products from unregulated websites.

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However, consult a doctor if you experience headache, dizziness, or nausea with the product.

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The FDA has approved a new herbal treatment that treats erectile dysfunction. The FDA approved it, known asViagra.

Viagra is a popular prescription medicine used to treat erectile dysfunction (ED), but the FDA approved it to treat sexual health problems in men. It belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors. These drugs help improve blood flow in the penis, which can help men with ED achieve and maintain an erection. However, there are risks to taking Viagra, including dangerously low blood pressure.

This article discusses the FDA’s approved prescription for Viagra, its effects and what to know about it.

What is Viagra?

Viagra, or sildenafil, is a prescription medicine used to treat erectile dysfunction (ED). This medication is an FDA-approved drug, and it is often used to treat men who suffer from erectile dysfunction due to insufficient blood flow to their penis. This medicine works by relaxing the muscles in the blood vessels in the penis, increasing blood flow, and helping men achieve and maintain an erection. Viagra is available only with a prescription from a doctor. It’s important to talk to your doctor before taking Viagra to ensure it’s right for you.

How Does Viagra Work?

Viagra works by inhibiting the PDE5 enzyme, which plays a key role in regulating blood flow. The active ingredient, sildenafil, belongs to a class of drugs known as PDE5 inhibitors, which work by blocking the breakdown of the active ingredient, PDE5. This action helps to increase the blood flow in the penis, which helps to achieve and maintain an erection.

Viagra also contains sildenafil, which works by relaxing the blood vessels in the penis, allowing for increased blood flow. This medication is typically taken by mouth once a day. The drug works by inhibiting the enzyme phosphodiesterase type 5 (PDE5) that breaks down the chemical in the blood vessels. This action helps to relax the blood vessels, allowing for increased blood flow. Viagra can be taken with or without food.

Before taking Viagra, be sure to inform your doctor if you are taking any other medications, including nitrate medications for chest pain, as these can interfere with how Viagra works. This medication should only be taken under the guidance of a medical professional.

What are the Common Side Effects of Viagra?

Viagra is generally well-tolerated, with the most common side effects reported by roughly 20% of patients. The most common side effects reported by about 8% to 10% of patients included headache, flushing, nasal congestion, back pain, and indigestion. However, more serious side effects may occur, including priapism, sudden vision loss, hearing loss, and heart problems. Viagra can cause serious side effects in rare cases, including priapism (prolonged and painful erection), sudden hearing loss, and hearing loss. Patients should be advised to report any of these side effects to their healthcare provider.

Viagra can also cause a dangerous drop in blood pressure, which can be dangerous if not taken as directed. Patients should be aware of these potential side effects and report them to their doctor immediately. If any of these side effects persist or worsen, immediately contact your doctor. If you experience any unusual symptoms, such as chest pain, sudden vision loss, or sudden hearing loss, contact your healthcare provider immediately.

What Are the Warnings of Viagra?

Viagra is not approved for use in children. However, its use is restricted to men under the age of 18 years. Viagra is not prescribed for use in women. The FDA has not approved Viagra for use in women, as there are safety concerns regarding the safety of this medication.

How Long Does Viagra Take to Work?

Viagra begins working within 30 minutes to an hour after ingestion. However, it may take up to six hours for the effects of Viagra to start working. Viagra may take effect in around 1 hour after ingestion.

The German-Swedish drugmaker, which will be based in Germany, has announced it will buy the country's first-ever "Viagra" pill, Pfizer's blockbuster erectile dysfunction pill Viagra, from the United States.

The deal follows an acquisition by Bayer of Pfizer, which in April sold the US market for 100 milligram Viagra to Germany's Bayer AG.

The transaction will be announced at a conference call with German-Swedish executives and German-speaking staff, said Bayer's chief executive, Karl-Nicolle Herrmann. The German company has already agreed to buy Pfizer's remaining stake in the US market for the first time for Viagra.

"Viagra is the most famous treatment for ED, and we've been very interested in the Viagra patent for the last few years," said the pharmaceutical company's chairman and chief executive, Matthias Herrmann. "This is a step forward in our relationship, and I know the importance of this acquisition for the German industry."

Viagra's patent was challenged last year by Pfizer, which is facing patent losses from the US generic drug market.

"We've had very limited patent expirations in the past, but that doesn't mean that we're going to have to take a hit," Herrmann said.

Viagra has been an important player in pharmaceutical innovation since it was introduced in 1998 and is now the world's best-selling medicine.

As part of the deal, Bayer will buy Pfizer's US rights to the Viagra patent and also buy Pfizer's patent rights in the UK. The company will also acquire the US market for the drug and sell it for up to a total of £7 billion in cash and a limited stock option.

Kreutz-Tier 1 drugmaker Bayer will make its £1.35 billion ($2.10 billion) upfront payment in the deal, and a further £1.35 billion upfront payment in the US. The company's patent rights in the UK have already expired, so the deal will be open to new competitors as well.

Viagra will become the bestselling medicine in the US, with more than 1 million prescriptions written every month.

Photo Credit: Reuters

In addition to the acquisition, Pfizer is also investing in its new research and development (R& D) business.

In the US, Pfizer is the world's leading pharmaceutical company with a sales force of nearly 1.4 million people.

As part of the deal, Pfizer will purchase a US manufacturing facility in the United States, which will be used to develop its own branded products and produce generic versions of Viagra.

Pfizer will pay a $4.2 billion (per share) debt to Germany's GSK, which has already secured $6 billion in sales for Viagra.

The German company also bought a US facility at the German-Swedish border for $1.5 billion, in part to boost the company's product pipeline and expand its presence in the Middle East.

In addition to the acquisition, Bayer has also acquired a research and development business for the US company's product pipeline. This includes a clinical trial for a new anti-impotence drug, a novel treatment for erectile dysfunction, and a development on new anti-inflammatory and anti-cancer therapies.

Bayer also has a $4.4 billion (per share) debt to pay to US regulators about a dozen products that have been approved for marketing in the US for over a year. The company also has a US manufacturing facility in California, where it is developing the first-ever Viagra tablet for women.

For more than a year, the German-Swedish pharmaceutical company has been battling patent losses due to the US patent on Viagra, and is also facing an increase in patent losses from the US generic market.

Viagra will be available by prescription only, and will be available through Bayer's website,.

Viagra is manufactured in India by Pfizer, an innovation-driven company that is the world's second-biggest generic producer, after Pfizer's patent in 1998. The company is seeking to build a strong, profitable pipeline of products that will pipeline up to a full company.